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Increased risk of angina pectoris; LATER SLEEP TIMES(>22.0)

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Kishor Kumar Seth
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INTRODUCTION

Sleep timing is related to several risk factors for angina pectoris (AP), such as obesity and diabetes. This study was designed to evaluate the relationship between sleep timing and AP, specifically whether later bedtime was associated with AP in middle-aged and older adults.Later bedtimes (>22:00) were associated with an increased risk of angina pectoris.This community-based study[2] was based on the Sleep Heart Health Study cohort and included 4710 participants (45.9% men, aged 63.3 ± 11.0 years). Lifestyle and epidemiological information were obtained from baseline records. MORE POINT FOR CONSIDERATION-[1]

1-Increased risk for later bedtimes was the same for both weekdays and weekends

2-Later weekend wake-up times were associated with increased risk of angina pectoris.

Sleep timing and angina pectoris-STUDY

Out of the 474 participants in the study, 41% were women and 67% were male. Overall, the median age of the participants was 64 years. The prevalence of AP in the group was 19.9%. AP was assessed using the Framingham Risk Score, which takes into account several risk factors, including diabetes, obesity, hypertension, and smoking. Participants who slept less than six hours a night had an increased risk of developing AP by 37%, compared with participants who slept six hours or more per night. The overall risk of developing AP was 22.6% higher in people who slept less than 6 hours a night compared with those who slept six to 7 hours, and 24.9% higher in those who slept between 7 and 8 hours a night compared with those who slept between 8 and 9 hours a night.

The result of the studY

1_Middle-aged and older adults who started at a time later than 8pm (bedtime) reported more angina symptoms than those who started later (bedtime 8pm vs. 8am). Source: The Lancet What this study tells us: a) The bedtime may be an important predictor of AP in younger adults b) The time of awakening and going to sleep may be important in managing AP in older adults Based on this study, we recommend: * Sleeping only 6-8 hours daily in early childhood may be a risk factor for sleep apnea and other sleep disorders in middle-aged adults * Caffeine before bedtime is a strong risk factor for AP * Do not go to bed with an empty stomach. Eating before bedtime increases blood glucose and gastric activity before bedtime

2_Sleep timing and angina pectoris are common risk factors for stroke (11, 12). The relative importance of sleep disorders in early onset CVD has been debated. Previous studies have shown that daytime hours were significantly related to CV mortality among both men with a history or current cardiac event as well ASSAGE patients who had never previously developed the condition (13, 14). In this prospective study we hypothesized an association between sleeping problems and late night NREM vs DSD; however there was no evidence that any other differences existed when using dichotomous data types based on chronotype rather than sex at baseline from prior examination/survey purposes. We also did not find support by those analyse.

Association Between Late Bedtime and Diabetes Mellitus: A Large Community-Based Study

Risk factors for coronary heart disease (CHD).

whether these conditions contribute to CHDs in people with no previous history of atherosclerosis is uncertain. The association between cigarette smoking [14], alcohol consumption during adolescence [5], sedentary behaviors [15–17]. Therefore prospective studies were conducted using both continuous health questionnaires as well a structured interview format at baseline or follow-up time points that included cardiovascular risks such stress fractures, hypertension/hyperlipidemia etc. The generalizability across different populations needs more work but one important finding from recent cohort studies suggests that men who report higher levels o

How sleep timing is related to AP

Approximately 1 in 8 adults suffer from AP, a very common chest pain condition that often goes unnoticed. AP can cause pain when an artery constricts, forcing blood from the heart into the coronary arteries to provide oxygenated blood to the heart. Angina is a common symptom associated with AP. Sleep is important for maintaining heart health. It has been hypothesized that AP is a side effect of sleep disruption. Thus, it is possible that circadian misalignment due to shift work, jet lag, or other environmental factors could be a risk factor for AP. The purpose of this study Using self-reported sleep diaries, researchers examined the relationship between AP, sleep timing, and night time wake time.

Conclusion

Overall, there was a lower prevalence of AP in adults who reported earlier bedtimes. Sleep onset timing was also related to other risk factors for AP, such as BMI, sleep apnea, hypertension, smoking, chronic pain, depression, and anxiety. This study showed an association between AP and sleep timing. Mature adults that reported later sleep timing were younger, healthier, had lower blood pressure, smoked less, were less depressed, and slept more. However, the results were unclear in this sample because they were based on self-reported data. The study also did not address the timing of sleep, and if anything, sleep duration appeared to be related to AP in older adults. Overall, this is an interesting study.Later bedtimes on both weekdays and weekends were significantly associated with an increased prevalence of AP. Early bedtimes may help people decrease the risk of AP.


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Kishor Kumar Seth

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